2WCX
Crystal Structure of Hepatitis C Virus NS5B Polymerase in Complex with Thienopyrrole-Based Finger-Loop Inhibitors
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | RNA-DIRECTED RNA POLYMERASE | polymer | 537 | 59772.7 | 1 | UniProt (P26663) Pfam (PF00998) | HEPATITIS C VIRUS | HEPATITIS C VIRUS RNA-DEPENDENT-RNA-POLYMERASE, NS5B, P68 |
| 2 | B, C (A) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 3 | D (A) | 6-CYCLOHEXYL-4-METHYL-5-PHENYL-4H-THIENO[3,2-B]PYRROLE-2-CARBOXYLIC ACID | non-polymer | 339.5 | 1 | Chemie (VGC) | |||
| 4 | E (A) | water | water | 18.0 | 507 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 59772.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 449.3 | |
| All* | Total formula weight | 60222.0 |
