2WA7

Structure of the M202V mutant of human filamin b actin binding domain at 1.85 Angstrom resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	FILAMIN-B	polymer	245	28103.1	1	UniProt (O75369) Pfam (PF00307)	HOMO SAPIENS (HUMAN)	M202V MUTANT FILAMIN B ACTIN-BINDING DOMAIN, FLN-B, TRUNCATED ABP, FH1, BETA-FILAMIN, ACTIN-BINDING-LIKE PROTEIN, THYROID AUTOANTIGEN, TRUNCATED ACTIN-BINDING PROTEIN, ABP-280 HOMOLOG, ABP-278, FILAMIN 3, FILAMIN HOMOLOG 1
2	B (A)	CACODYLATE ION	non-polymer		137.0	1	Chemie (CAC)
3	C, D, E (A)	CARBONATE ION	non-polymer		60.0	3	Chemie (CO3)
4	F (A)	water	water		18.0	204	Chemie (HOH)

Sequence modifications

A: -2 - 1 (PDB: 2WA7)
A: 2 - 242 (UniProt: O75369)

PDB	External Database	Details
Val 202	Met 202	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	28103.1
Non-Polymers*	Number of molecules	4
	Total formula weight	317.0
All*	Total formula weight	28420.1

*Water molecules are not included.