2WA6

Structure of the W148R mutant of human filamin b actin binding domain at 1.95 Angstrom resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	FILAMIN-B	polymer	245	28106.2	1	UniProt (O75369) Pfam (PF00307) In PDB	HOMO SAPIENS (HUMAN)	BETA-FILAMIN, ACTIN-BINDING-LIKE PROTEIN, THYROID AUTOANTIGEN, TRUNCATED ACTIN-BINDING PROTEIN, ABP-280 HOMOLOG, ABP-278, FILAMIN 3, FILAMIN HOMOLOG 1, FLN-B, TRUNCATED ABP, FH1, W148R MUTANT FILAMIN B ACTIN-BINDING DOMAIN
2	A	CARBONATE ION	non-polymer		60.0	2	Chemie (CO3)
3		water	water		18.0	159	Chemie (HOH)

Sequence modifications

A: -2 - 1 (PDB: 2WA6)
A: 2 - 242 (UniProt: O75369)

PDB	External Database	Details
Arg 148	Trp 148	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	28106.2
Non-Polymers*	Number of molecules	2
	Total formula weight	120.0
All*	Total formula weight	28226.2

*Water molecules are not included.