2WA2

Structure of the methyltransferase domain from Modoc Virus, a Flavivirus with No Known Vector (NKV)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	NON-STRUCTURAL PROTEIN 5	polymer	276	30812.2	2	UniProt (Q8QL64) Pfam (PF01728)	MODOC VIRUS	NS5 FROM MODOC VIRUS
2	C, E (A, B)	S-ADENOSYLMETHIONINE	non-polymer		398.4	2	Chemie (SAM)
3	D, F, G (A, B)	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
4	H, I (A, B)	water	water		18.0	298	Chemie (HOH)

Sequence modifications

A, B: -7 - 0 (PDB: 2WA2)
A, B: 1 - 268 (UniProt: Q8QL64)

PDB	External Database	Details
Thr 77	Ser 2553	engineered mutation
Ser 87	Gly 2563	engineered mutation
Thr 134	Arg 2610	engineered mutation
Ala 202	Arg 2678	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	61624.4
Non-Polymers*	Number of molecules	5
	Total formula weight	1085.1
All*	Total formula weight	62709.5

*Water molecules are not included.