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2W9G

Wild-type Staphylococcus aureus DHFR in complex with NADPH and trimethoprim

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DIHYDROFOLATE REDUCTASEpolymer15918275.91UniProt (P0A017)
Pfam (PF00186)
STAPHYLOCOCCUS AUREUSDHFR
2B
(A)
TRIMETHOPRIMnon-polymer290.31Chemie (TOP)
3C
(A)
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer745.41Chemie (NDP)
4D
(A)
waterwater18.086Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight18275.9
Non-Polymers*Number of molecules2
Total formula weight1035.7
All*Total formula weight19311.7
*Water molecules are not included.

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PDB entries from 2025-08-27

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