2W9E
Structure of ICSM 18 (anti-Prp therapeutic antibody) Fab fragment complexed with human Prp fragment 119-231
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | MAJOR PRION PROTEIN | polymer | 113 | 13231.7 | 1 | UniProt (P04156) Pfam (PF00377) | HOMO SAPIENS (HUMAN) | PRP27-30, PRP33-35C, ASCR, PRP |
| 2 | B (H) | ICSM 18-ANTI-PRP THERAPEUTIC FAB HEAVY CHAIN | polymer | 215 | 23045.6 | 1 | MUS MUSCULUS | ||
| 3 | C (L) | ICSM 18-ANTI-PRP THERAPEUTIC FAB LIGHT CHAIN | polymer | 212 | 23283.7 | 1 | MUS MUSCULUS | ||
| 4 | D (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | E, F, G (A, H, L) | water | water | 18.0 | 42 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 59561.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 96.1 | |
| All* | Total formula weight | 59657.0 |
