2W8R
The crystal structure of human SSADH in complex with NAD+
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL | polymer | 487 | 52258.6 | 1 | UniProt (P51649) Pfam (PF00171) | HOMO SAPIENS (HUMAN) | SUCCINIC SEMIALDEHYDE DEHYDROGENASE, NAD(+)-DEPENDENT SUCCINIC SEMIALDEHYDE DEHYDROGENASE, ALDEHYDE DEHYDROGENASE FAMILY 5 MEMBER A1 |
| 2 | B (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 3 | C, D, E, F, G... (A) | SULFATE ION | non-polymer | 96.1 | 10 | Chemie (SO4) | |||
| 4 | M, N (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | O (A) | water | water | 18.0 | 48 | Chemie (HOH) |
Sequence modifications
A: 49 - 535 (UniProt: P51649)
| PDB | External Database | Details |
|---|---|---|
| Ala 340 | Cys 340 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 52258.6 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1572.0 | |
| All* | Total formula weight | 53830.6 |
