2W81

Structure of a complex between Neisseria meningitidis factor H binding protein and CCPs 6-7 of human complement factor H

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, E (A, B, E)	COMPLEMENT FACTOR H	polymer	123	14222.0	3	UniProt (P08603) Pfam (PF00084)	HOMO SAPIENS (HUMAN)	H FACTOR 1
2	C, D, F (C, D, F)	FACTOR H BINDING PROTEIN	polymer	253	26983.1	3	UniProt (Q9JXV4) Pfam (PF20937) Pfam (PF08794)	NEISSERIA MENINGITIDIS
3	G, H, I, J, K... (A, B, C, D, E...)	water	water		18.0	424	Chemie (HOH)

Sequence modifications

A, B, E: 321 - 443 (UniProt: P08603)

PDB	External Database	Details
His 402	Tyr 402	variant

C, D, F: 71 - 320 (UniProt: Q9JXV4)
C, D, F: 321 - 323 (PDB: 2W81)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	123615.3
All*	Total formula weight	123615.3

*Water molecules are not included.