2W79
Establishing wild-type levels of catalytic activity on natural and artificial (ba)8-barrel protein scaffolds
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 1-(5-PHOSPHORIBOSYL)-5-[(5-PHOSPHORIBOSYLAMINO) METHYLIDENEAMINO] IMIDAZOLE-4-CARBOXAMIDE ISOMERASE | polymer | 241 | 27001.3 | 2 | UniProt (Q9X0C7) Pfam (PF00977) | THERMOTOGA MARITIMA | PHOSPHORIBOSYLFORMIMINO-5-AMINOIMIDAZOLE CARBOXAMIDE RIBOTIDE ISOMERASE, N-PHOSPHORIBOSYL-FORMIMINO-AMINOIMIDAZOL-CARBOXAMID RIBONUCLEOTID ISOMERASE |
| 2 | C (B) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 3 | D, E (A, B) | water | water | 18.0 | 378 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 241 (UniProt: Q9X0C7)
| PDB | External Database | Details |
|---|---|---|
| Tyr 75 | His 75 | engineered mutation |
| Ser 111 | Phe 111 | engineered mutation |
| Val 127 | Asp 127 | engineered mutation |
| Val 169 | Asp 169 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 54002.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 35.5 | |
| All* | Total formula weight | 54038.0 |
