2W79

Establishing wild-type levels of catalytic activity on natural and artificial (ba)8-barrel protein scaffolds

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000105	biological_process	L-histidine biosynthetic process
A	0000162	biological_process	tryptophan biosynthetic process
A	0003949	molecular_function	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity
A	0005737	cellular_component	cytoplasm
A	0016853	molecular_function	isomerase activity
B	0000105	biological_process	L-histidine biosynthetic process
B	0000162	biological_process	tryptophan biosynthetic process
B	0003949	molecular_function	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity
B	0005737	cellular_component	cytoplasm
B	0016853	molecular_function	isomerase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL B1242

Chain	Residue
B	GLY170
B	ARG224

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Proton acceptor => ECO:0000305|PubMed:12356303

Chain	Residue	Details
A	ASP8
B	ASP8

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site_id	SWS_FT_FI2
Number of Residues	2
Details	ACT_SITE: Proton donor => ECO:0000305|PubMed:12356303

Chain	Residue	Details
A	VAL127
B	VAL127

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