2W36

Structures of endonuclease V with DNA reveal initiation of deaminated adenine repair

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	ENDONUCLEASE V	polymer	225	25591.9	2	UniProt (Q9X2H9) Pfam (PF04493)	THERMOTOGA MARITIMA	DEOXYINOSINE 3'ENDONUCLEASE, DEOXYRIBONUCLEASE V, DNASE V
2	C, E (C, E)	5'-D(*GP*CP*BRUP*AP*CP*IP*GP*AP*BRUP*CP*GP)-3'	polymer	11	3488.9	2		synthetic construct
3	D, F (D, F)	5'-D(*CP*GP*AP*TP*CP*TP*GP*TP*AP*GP*CP)-3'	polymer	11	3349.2	2		synthetic construct
4	G, H, I, J, K (A, B, C, E, F)	water	water		18.0	221	Chemie (HOH)

Sequence modifications

A, B: 1 - 225 (UniProt: Q9X2H9)

PDB	External Database	Details
Ala 43	Asp 43	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	64860.1
All*	Total formula weight	64860.1

*Water molecules are not included.