2W1I

Structure determination of Aurora Kinase in complex with inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	JAK2	polymer	326	38589.6	2	UniProt (O60674) Pfam (PF07714)	HOMO SAPIENS (HOMO SAPIENS)
2	C (A)	4-[(2-{4-[(CYCLOPROPYLCARBAMOYL)AMINO]-1H-PYRAZOL-3-YL}-1H-BENZIMIDAZOL-6-YL)METHYL]MORPHOLIN-4-IUM	non-polymer		382.4	1	Chemie (L0I)
3	D, E (A, B)	water	water		18.0	131	Chemie (HOH)

Sequence modifications

A, B: 807 - 834 (PDB: 2W1I)
A, B: 835 - 1132 (UniProt: O60674)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	77179.3
Non-Polymers*	Number of molecules	1
	Total formula weight	382.4
All*	Total formula weight	77561.7

*Water molecules are not included.