2W1I
Structure determination of Aurora Kinase in complex with inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | JAK2 | polymer | 326 | 38589.6 | 2 | UniProt (O60674) Pfam (PF07714) In PDB | HOMO SAPIENS (HOMO SAPIENS) | |
2 | A | 4-[(2-{4-[(CYCLOPROPYLCARBAMOYL)AMINO]-1H-PYRAZOL-3-YL}-1H-BENZIMIDAZOL-6-YL)METHYL]MORPHOLIN-4-IUM | non-polymer | 382.4 | 1 | Chemie (L0I) | |||
3 | water | water | 18.0 | 131 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 77179.3 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 382.4 | |
All* | Total formula weight | 77561.7 |