2W1I

Structure determination of Aurora Kinase in complex with inhibitor

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	ROTATING ANODE
Temperature [K]	100
Spacegroup name	C 1 2 1
Unit cell lengths	102.757, 93.129, 123.269
Unit cell angles	90.00, 146.58, 90.00

Refinement procedure

Resolution	29.720 - 2.600
R-factor	0.209
Rwork	0.204
R-free	0.29500
Structure solution method	OTHER
Starting model (for MR)	NONE
RMSD bond length	0.012
RMSD bond angle	1.448
Refinement software	REFMAC (5.2.0019F)

Data quality characteristics

	Overall
Low resolution limit [Å]	29.720
High resolution limit [Å]	2.600
Rmerge	0.070
Number of reflections	18561
<I/σ(I)>	8.3
Completeness [%]	99.0
Redundancy	2.18

Crystallization Conditions

crystal ID	method	pH	temperature	details
1