2W1G
Structure determination of Aurora Kinase in complex with inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | SERINE/THREONINE-PROTEIN KINASE 6 | polymer | 275 | 32317.9 | 1 | UniProt (O14965) Pfam (PF00069) | HOMO SAPIENS (HUMAN) | AURORA KINASE A, SERINE/THREONINE KINASE 15, AURORA/IPL1-RELATED KINASE 1, BREAST TUMOR-AMPLIFIED KINASE, AURORA A, AURORA-A, AURORA-RELATED KINASE 1, HARK1 |
| 2 | B (A) | 2-{4-[(CYCLOPROPYLCARBAMOYL)AMINO]-1H-PYRAZOL-3-YL}-6-(MORPHOLIN-4-IUM-4-YLMETHYL)-1H-3,1-BENZIMIDAZOL-3-IUM | non-polymer | 383.4 | 1 | Chemie (L0G) | |||
| 3 | C (A) | water | water | 18.0 | 26 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32317.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 383.4 | |
| All* | Total formula weight | 32701.3 |
