2W1F

Structure determination of Aurora Kinase in complex with inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	SERINE/THREONINE-PROTEIN KINASE 6	polymer	275	32157.9	1	UniProt (O14965) Pfam (PF00069) In PDB	HOMO SAPIENS (HUMAN)	AURORA KINASE A, SERINE/THREONINE KINASE 15, AURORA/IPL1-RELATED KINASE 1, BREAST TUMOR-AMPLIFIED KINASE, AURORA A, AURORA-A, AURORA-RELATED KINASE 1, HARK1
2	A	N-[3-(1H-BENZIMIDAZOL-2-YL)-1H-PYRAZOL-4-YL]BENZAMIDE	non-polymer		303.3	1	Chemie (L0F)
3		water	water		18.0	30	Chemie (HOH)

Sequence modifications

A: 121 - 121 (PDB: 2W1F)
A: 390 - 395 (PDB: 2W1F)
A: 122 - 389 (UniProt: O14965)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	32157.9
Non-Polymers*	Number of molecules	1
	Total formula weight	303.3
All*	Total formula weight	32461.3

*Water molecules are not included.