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2VZ6

Structure of human calcium calmodulin dependent protein kinase type II alpha (CAMK2A) in complex with Indirubin E804

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BCALCIUM CALMODULIN DEPENDENT PROTEIN KINASE TYPE II ALPHA CHAINpolymer31335641.92UniProt (Q9UQM7)
Pfam (PF00069)
In PDB
HOMO SAPIENS (HUMAN)CAM-KINASE II ALPHA CHAIN, CAM KINASE II SUBUNIT ALPHA, CAMK-II SUBUNIT ALPHA
2A, B(2Z,3E)-2,3'-BIINDOLE-2',3(1H,1'H)-DIONE 3-{O-[(3R)-3,4-DIHYDROXYBUTYL]OXIME}non-polymer365.42Chemie (FEF)
3A, BS-1,2-PROPANEDIOLnon-polymer76.13Chemie (PGO)
4waterwater18.0311Chemie (HOH)
Sequence modifications
A, B: -22 - 0 (PDB: 2VZ6)
A, B: 13 - 302 (UniProt: Q9UQM7)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight71283.8
Non-Polymers*Number of molecules5
Total formula weight959.0
All*Total formula weight72242.8
*Water molecules are not included.

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PDB entries from 2024-07-24

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