2VZ6

Structure of human calcium calmodulin dependent protein kinase type II alpha (CAMK2A) in complex with Indirubin E804

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE TYPE II ALPHA CHAIN	polymer	313	35641.9	2	UniProt (Q9UQM7) Pfam (PF00069)	HOMO SAPIENS (HUMAN)	CAM-KINASE II ALPHA CHAIN, CAM KINASE II SUBUNIT ALPHA, CAMK-II SUBUNIT ALPHA
2	C, F (A, B)	(2Z,3E)-2,3'-BIINDOLE-2',3(1H,1'H)-DIONE 3-{O-[(3R)-3,4-DIHYDROXYBUTYL]OXIME}	non-polymer		365.4	2	Chemie (FEF)
3	D, E, G (A, B)	S-1,2-PROPANEDIOL	non-polymer		76.1	3	Chemie (PGO)
4	H, I (A, B)	water	water		18.0	311	Chemie (HOH)

Sequence modifications

A, B: -22 - 0 (PDB: 2VZ6)
A, B: 13 - 302 (UniProt: Q9UQM7)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	71283.8
Non-Polymers*	Number of molecules	5
	Total formula weight	959.0
All*	Total formula weight	72242.8

*Water molecules are not included.