2VUM
Alpha-amanitin inhibited complete RNA polymerase II elongation complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 | polymer | 1733 | 191821.6 | 1 | UniProt (P04050) Pfam (PF04997) Pfam (PF05001) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) Pfam (PF04992) Pfam (PF04990) In PDB | SACCHAROMYCES CEREVISIAE (BAKERS' YEAST) | RNA POLYMERASE II SUBUNIT B1, RNA POLYMERASE II SUBUNIT 1, DNA-DIRECTED RNA POLYMERASE III LARGEST SUBUNIT, B220, DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT |
| 2 | B | DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2 | polymer | 1224 | 138937.3 | 1 | UniProt (P08518) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF04566) Pfam (PF04567) Pfam (PF00562) Pfam (PF04560) In PDB | SACCHAROMYCES CEREVISIAE (BAKERS' YEAST) | DNA-DIRECTED RNA POLYMERASE II 140 KDA, RNA POLYMERASE II SUBUNIT 2, DNA-DIRECTED RNA POLYMERASE II 140 KDA POLYPEPTIDE, B150 POLYPEPTIDE |
| 3 | C | DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3 | polymer | 318 | 35330.5 | 1 | UniProt (P16370) Pfam (PF01193) Pfam (PF01000) In PDB | SACCHAROMYCES CEREVISIAE (BAKERS' YEAST) | DNA-DIRECTED RNA POLYMERASE II 45 KDA POLYPEPTIDE, RNA POLYMERASE II SUBUNIT B3, RNA POLYMERASE II SUBUNIT 3, DNA-DIRECTED RNA POLYMERASE II 45 KDA POLYPEPTIDE, B445. |
| 4 | D | DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB4 | polymer | 221 | 25451.2 | 1 | UniProt (P20433) Pfam (PF03874) In PDB | SACCHAROMYCES CEREVISIAE (BAKERS' YEAST) | DNA-DIRECTED RNA POLYMERASE II 32 KDA POLYPEPTIDE, RNA POLYMERASE II SUBUNIT B4, DNA-DIRECTED RNA POLYMERASE II 32 KDA POLYPEPTIDE, B32 |
| 5 | E | DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC1 | polymer | 215 | 25117.1 | 1 | UniProt (P20434) Pfam (PF03871) Pfam (PF01191) In PDB | SACCHAROMYCES CEREVISIAE (BAKERS' YEAST) | DNA-DIRECTED RNA POLYMERASES I, II, AND III 27 KDA POLYPEPTIDE, RNA POLYMERASES I, II, AND III SUBUNIT ABC1, DNA-DIRECTED RNA POLYMERASES I, II, AND III 27 KDA POLYPEPTIDE, ABC27 |
| 6 | F | DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC2 | polymer | 155 | 17931.8 | 1 | UniProt (P20435) Pfam (PF01192) In PDB | SACCHAROMYCES CEREVISIAE (BAKERS' YEAST) | DNA-DIRECTED RNA POLYMERASES I, II, AND III 23 KDA POLYPEPTIDE, RNA POLYMERASES I, II, AND III SUBUNIT ABC2, DNA-DIRECTED RNA POLYMERASES I, II, AND III 23 KDA POLYPEPTIDE, ABC23 |
| 7 | G | DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB7 | polymer | 171 | 19081.1 | 1 | UniProt (P34087) Pfam (PF03876) Pfam (PF00575) In PDB | SACCHAROMYCES CEREVISIAE (BAKERS' YEAST) | DNA-DIRECTED RNA POLYMERASE II 19 KDA POLYPEPTIDE, RNA POLYMERASE II SUBUNIT B7, B16 |
| 8 | H | DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC3 | polymer | 146 | 16525.4 | 1 | UniProt (P20436) Pfam (PF03870) In PDB | SACCHAROMYCES CEREVISIAE (BAKERS' YEAST) | DNA-DIRECTED RNA POLYMERASES I, II, AND III 14.5 KDA POLYPEPTIDE, RNA POLYMERASES I, II, AND III SUBUNIT ABC3, DNA-DIRECTED RNA POLYMERASES I, II, AND III 145 KDA POLYPEPTIDE, ABC144, ABC145 |
| 9 | I | DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB9 | polymer | 122 | 14308.2 | 1 | UniProt (P27999) Pfam (PF02150) Pfam (PF01096) In PDB | SACCHAROMYCES CEREVISIAE (BAKERS' YEAST) | DNA-DIRECTED RNA POLYMERASE II SUBUNIT 9, RNA POLYMERASE II SUBUNIT B9, DNA-DIRECTED RNA POLYMERASE II SUBUNIT 9, DNA-DIRECTED RNA POLYMERASE II 142 KDA POLYPEPTIDE, B126 |
| 10 | J | DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC5 | polymer | 70 | 8290.7 | 1 | UniProt (P22139) Pfam (PF01194) In PDB | SACCHAROMYCES CEREVISIAE (BAKERS' YEAST) | DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT 10, RNA POLYMERASES I, II, AND III SUBUNIT ABC5, DNA-DIRECTED RNA POLYMERASES I, II, AND III 83 KDA POLYPEPTIDE, ABC10-BETA, ABC8 |
| 11 | K | DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11 | polymer | 120 | 13633.5 | 1 | UniProt (P38902) Pfam (PF13656) Pfam (PF01193) In PDB | SACCHAROMYCES CEREVISIAE (BAKERS' YEAST) | DNA-DIRECTED RNA POLYMERASE II 13.6 KDA POLYPEPTIDE, RNA POLYMERASE II SUBUNIT B11, DNA-DIRECTED RNA POLYMERASE II 136 KDA POLYPEPTIDE, B136 |
| 12 | L | DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC4 | polymer | 70 | 7730.0 | 1 | UniProt (P40422) Pfam (PF03604) In PDB | SACCHAROMYCES CEREVISIAE (BAKERS' YEAST) | DNA-DIRECTED RNA POLYMERASES I, II, AND III 7.7 KDA POLYPEPTIDE, RNA POLYMERASES I, II, AND III SUBUNIT ABC4, ABC10-ALPHA |
| 13 | M | AMATOXIN | polymer | 8 | 939.0 | 1 | UniProt (P85421) In PDB | AMANITA PHALLOIDES (DEATH CAP) | ALPHA AMANITIN, GAMMA-AMANITIN |
| 14 | N | 5'-D(*AP*AP*AP*CP*TP*AP*CP*TP*TP*GP *AP*GP*CP*T)-3' | polymer | 14 | 4263.8 | 1 | synthetic construct | NONTEMPLATE DNA | |
| 15 | P | 5'-R(*AP*AP*AP*GP*AP*CP*CP*AP*GP*GP*C)-3' | polymer | 11 | 3552.2 | 1 | synthetic construct | PRODUCT RNA | |
| 16 | T | 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP *GP*TP*TP*AP*CP*GP*CP*CP*BRUP*GP*GP*TP*CP*AP*TP*T)-3' | polymer | 26 | 8043.0 | 1 | synthetic construct | TEMPLATE DNA | |
| 17 | A, B, C, I, J... | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
| 18 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 16 |
| Total formula weight | 530956.3 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 547.6 | |
| All* | Total formula weight | 531503.9 |
