2VR7

Crystal Structure of G85R ALS mutant of Human Cu,Zn Superoxide Dismutase (CuZnSOD) at 1.58 A resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, F)	SUPEROXIDE DISMUTASE [CU-ZN]	polymer	154	15953.7	2	UniProt (P00441) Pfam (PF00080)	HOMO SAPIENS (HUMAN)
2	C, K (A, F)	COPPER (II) ION	non-polymer		63.5	2	Chemie (CU)
3	D, E, G, J, L... (A, F)	ZINC ION	non-polymer		65.4	6	Chemie (ZN)
4	F, N (A, F)	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
5	H, I, O, P (A, F)	THIOCYANATE ION	non-polymer		58.1	4	Chemie (SCN)
6	Q, R (A, F)	water	water		18.0	624	Chemie (HOH)

Sequence modifications

A, F: 0 - 0 (PDB: 2VR7)
A, F: 1 - 153 (UniProt: P00441)

PDB	External Database	Details
Arg 85	Gly 86	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	31907.5
Non-Polymers*	Number of molecules	14
	Total formula weight	944.0
All*	Total formula weight	32851.5

*Water molecules are not included.