2VQZ
Structure of the cap-binding domain of influenza virus polymerase subunit PB2 with bound m7GTP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (A, B, D, E, F) | POLYMERASE BASIC PROTEIN 2 | polymer | 166 | 19316.9 | 5 | UniProt (P31345) Pfam (PF00604) | INFLUENZA A VIRUS | RNA-DIRECTED RNA POLYMERASE SUBUNIT P3, PB2 CAP-BINDING DOMAIN |
| 2 | F, G, H, I, J (A, B, D, E, F) | 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE | non-polymer | 539.2 | 5 | Chemie (MGT) | |||
| 3 | K, L, M, N, O (A, B, D, E, F) | water | water | 18.0 | 272 | Chemie (HOH) |
Sequence modifications
A, B, D, E, F: 318 - 483 (UniProt: P31345)
| PDB | External Database | Details |
|---|---|---|
| Lys 389 | Arg 389 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 96584.4 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 2696.1 | |
| All* | Total formula weight | 99280.5 |
