2VQJ

Structure of HDAC4 catalytic domain bound to a trifluoromethylketone inhbitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	HISTONE DEACETYLASE 4	polymer	413	44477.4	1	UniProt (P56524) Pfam (PF00850) In PDB	HOMO SAPIENS (HUMAN)	HD4
2	A	1,4-DIETHYLENE DIOXIDE	non-polymer		88.1	1	Chemie (DIO)
3	A	POTASSIUM ION	non-polymer		39.1	2	Chemie (K)
4	A	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
5	A	2,2,2-TRIFLUORO-1-{5-[(3-PHENYL-5,6-DIHYDROIMIDAZO[1,2-A]PYRAZIN-7(8H)-YL)CARBONYL]THIOPHEN-2-YL}ETHANE-1,1-DIOL	non-polymer		423.4	1	Chemie (TFG)
6	A	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
7		water	water		18.0	222	Chemie (HOH)

Sequence modifications

A: 1 - 3 (PDB: 2VQJ)
A: 4 - 413 (UniProt: P56524)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	44477.4
Non-Polymers*	Number of molecules	9
	Total formula weight	1008.7
All*	Total formula weight	45486.1

*Water molecules are not included.