2VPG

Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	PYGOPUS HOMOLOG 1	polymer	63	6759.6	2	UniProt (Q9Y3Y4) Pfam (PF00628)	HOMO SAPIENS (HUMAN)	HPYGO1
2	B, D (B, D)	B-CELL CLL/LYMPHOMA 9 PROTEIN	polymer	32	3445.0	2	UniProt (O00512)	HOMO SAPIENS (HUMAN)	B-CELL LYMPHOMA 9 PROTEIN, BCL-9, PROTEIN LEGLESS HOMOLOG, BCL9
3	E, F (P, R)	HISTONE H3 TAIL	polymer	18	2003.4	2	UniProt (by SIFTS) (P68431)	HOMO SAPIENS
4	G (A)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
5	H, I, J, K (A, C)	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
6	L, M, N, O, P... (A, B, C, D, P...)	water	water		18.0	259	Chemie (HOH)

Sequence modifications

A, C: 336 - 339 (PDB: 2VPG)
A, C: 340 - 398 (UniProt: Q9Y3Y4)
B, D: 174 - 176 (PDB: 2VPG)
B, D: 177 - 205 (UniProt: O00512)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	24416.0
Non-Polymers*	Number of molecules	5
	Total formula weight	353.7
All*	Total formula weight	24769.7

*Water molecules are not included.