2VP7
Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PYGOPUS HOMOLOG 1 | polymer | 71 | 7661.5 | 1 | UniProt (Q9Y3Y4) Pfam (PF00628) | HOMO SAPIENS (HUMAN) | HPYGO1 |
| 2 | B (B) | B-CELL CLL/LYMPHOMA 9 PROTEIN | polymer | 33 | 3556.1 | 1 | UniProt (O00512) | HOMO SAPIENS (HUMAN) | B-CELL LYMPHOMA 9 PROTEIN, BCL-9, PROTEIN LEGLESS HOMOLOG, BCL9 |
| 3 | C, F, G (A, B) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 4 | D, E (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 99 | Chemie (HOH) |
Sequence modifications
A: 332 - 332 (PDB: 2VP7)
A: 333 - 402 (UniProt: Q9Y3Y4)
B: 173 - 173 (PDB: 2VP7)
B: 174 - 205 (UniProt: O00512)
A: 333 - 402 (UniProt: Q9Y3Y4)
| PDB | External Database | Details |
|---|---|---|
| Phe 366 | Trp 366 | engineered mutation |
B: 174 - 205 (UniProt: O00512)
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 11217.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 419.0 | |
| All* | Total formula weight | 11636.7 |
