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2VP7

Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex

Functional Information from GO Data
ChainGOidnamespacecontents
B0003713molecular_functiontranscription coactivator activity
B0008013molecular_functionbeta-catenin binding
B0060070biological_processcanonical Wnt signaling pathway
Functional Information from PDB Data
site_idAC1
Number of Residues2
DetailsBINDING SITE FOR RESIDUE SO4 B1206
ChainResidue
BTYR178
BPHE203

site_idAC2
Number of Residues4
DetailsBINDING SITE FOR RESIDUE SO4 A1398
ChainResidue
AHIS334
AVAL350
AALA356
APHE366

site_idAC3
Number of Residues5
DetailsBINDING SITE FOR RESIDUE SO4 B1207
ChainResidue
BHOH1038
BHOH1039
BLYS175
BHOH1036
BHOH1037

site_idAC4
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN A1399
ChainResidue
ACYS343
ACYS346
AHIS368
ACYS371

site_idAC5
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN A1400
ChainResidue
ACYS359
ACYS363
ACYS392
ACYS395

Functional Information from PROSITE/UniProt
site_idPS01359
Number of Residues53
DetailsZF_PHD_1 Zinc finger PHD-type signature. CgiCtnevnddqda...................................IlCeas.Cqkf.FHriCtgmtetayglltaeasav...........................WgCdtC
ChainResidueDetails
ACYS343-CYS395

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues58
DetailsZN_FING: PHD-type => ECO:0000255|PROSITE-ProRule:PRU00146
ChainResidueDetails
AVAL340-ASP398

227111

PDB entries from 2024-11-06

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