2VN9

Crystal Structure of Human Calcium Calmodulin dependent Protein Kinase II delta isoform 1, CAMKD

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II DELTA CHAIN	polymer	301	34253.5	2	UniProt (Q13557) Pfam (PF00069)	Homo sapiens (human)	CAM-KINASE II DELTA CHAIN, CAM KINASE II SUBUNIT DELTA, CAMK-II SUBUNIT DELTA, CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II DELTA ISOFORM 1
2	C, D, I, J (A, B)	PHOSPHATE ION	non-polymer		95.0	4	Chemie (PO4)
3	E (A)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
4	F (A)	4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID	non-polymer		238.3	1	Chemie (EPE)
5	G, H (A, B)	[4-({4-[(5-CYCLOPROPYL-1H-PYRAZOL-3-YL)AMINO]QUINAZOLIN-2-YL}IMINO)CYCLOHEXA-2,5-DIEN-1-YL]ACETONITRILE	non-polymer		381.4	2	Chemie (GVD)
6	K, L (A, B)	water	water		18.0	97	Chemie (HOH)

Sequence modifications

A, B: -1 - 0 (PDB: 2VN9)
A, B: 11 - 309 (UniProt: Q13557)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	68506.9
Non-Polymers*	Number of molecules	8
	Total formula weight	1416.5
All*	Total formula weight	69923.4

*Water molecules are not included.