2VMY
Crystal structure of F351GbsSHMT in complex with Gly and FTHF
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | SERINE HYDROXYMETHYLTRANSFERASE | polymer | 405 | 44184.1 | 2 | UniProt (Q7SIB6) Pfam (PF00464) In PDB | BACILLUS STEAROTHERMOPHILUS | SHMT, SERINE METHYLASE |
| 2 | A, B | GLYCINE | non-polymer | 75.1 | 2 | Chemie (GLY) | |||
| 3 | A, B | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 2 | Chemie (PLP) | |||
| 4 | A, B | N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid | non-polymer | 473.4 | 2 | Chemie (FFO) | |||
| 5 | B | (4R)-2-METHYLPENTANE-2,4-DIOL | non-polymer | 118.2 | 1 | Chemie (MRD) | |||
| 6 | water | water | 18.0 | 24 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 405 (UniProt: Q7SIB6)
| PDB | External Database | Details |
|---|---|---|
| Gly 351 | Phe 351 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 88368.1 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1709.5 | |
| All* | Total formula weight | 90077.6 |
