2VIS

INFLUENZA VIRUS HEMAGGLUTININ, (ESCAPE) MUTANT WITH THR 131 REPLACED BY ILE, COMPLEXED WITH A NEUTRALIZING ANTIBODY

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	IMMUNOGLOBULIN (IGG1, LAMBDA)	polymer	210	22596.0	1	GenBank (387376)	Mus musculus (house mouse)
2	B (B)	IMMUNOGLOBULIN (IGG1, LAMBDA)	polymer	221	23777.8	1	GenBank (4096752) Pfam (PF07686) Pfam (PF07654) UniProt (by SIFTS) (Q99LC4)	Mus musculus (house mouse)
3	C (C)	HEMAGGLUTININ	polymer	282	31176.0	1	UniProt (P03437) Pfam (PF00509)	Influenza A virus (A/X-31(H3N2))
4	D, E, G (A, C)	ZINC ION	non-polymer		65.4	3	Chemie (ZN)
5	F (C)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)

Sequence modifications

B: 1 - 221 (GenBank: 4096752)

PDB	External Database	Details
Gln 3	Lys 3	conflict
Lys 5	Gln 5	conflict
Leu 28	Ser 28	conflict
Ile 30	Thr 30	conflict
Asn 32	Tyr 32	conflict
Leu 63	His 63	conflict
Ile 69	Phe 69	conflict
Lys 83	Asn 83	conflict
Met 92	Leu 92	conflict
Asp 98	-	insertion
Phe 99	-	insertion
Tyr 100	-	insertion
Tyr 102	His 99	conflict
Asp 103	Gly 100	conflict
Phe 105	-	insertion
Tyr 106	-	insertion
Tyr 107	-	insertion
Ala 108	-	insertion
Met 109	-	insertion
Asp 110	-	insertion
Ser 117	Leu 108	conflict
Ser 122	Ala 113	conflict
Pro 135	Ser 126	conflict

C: 28 - 309 (UniProt: P03437)

PDB	External Database	Details
Ile 131	Thr 147	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	77549.8
Non-Polymers*	Number of molecules	4
	Total formula weight	417.4
All*	Total formula weight	77967.2

*Water molecules are not included.