2VGP
Crystal structure of Aurora B kinase in complex with a aminothiazole inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | SERINE/THREONINE-PROTEIN KINASE 12-A | polymer | 284 | 33537.9 | 2 | UniProt (Q6DE08) Pfam (PF00069) | XENOPUS LAEVIS (AFRICAN CLAWED FROG) | AURORA B KINASE, AURORA-B-A, AURORA/IPL1-RELATED KINASE 2-A, AIRK2-A |
| 2 | C, D (C, D) | INNER CENTROMERE PROTEIN A | polymer | 43 | 4976.6 | 2 | UniProt (O13024) Pfam (PF03941) | XENOPUS LAEVIS (AFRICAN CLAWED FROG) | MITOTIC PHOSPHOPROTEIN 130, XL-INCENP |
| 3 | E, F (A, B) | 4-[(5-bromo-1,3-thiazol-2-yl)amino]-N-methylbenzamide | non-polymer | 312.2 | 2 | Chemie (AD6) | |||
| 4 | G, H, I, J (A, B, C, D) | water | water | 18.0 | 729 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 77029.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 624.4 | |
| All* | Total formula weight | 77653.4 |
