2VFZ

CRYSTAL STRUCTURE OF ALPHA-1,3 GALACTOSYLTRANSFERASE (R365K) IN COMPLEX WITH UDP-2F-GALACTOSE

Replaces:  2JCF

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYL TRANSFERASE	polymer	289	34062.1	2	UniProt (P14769) Pfam (PF03414)	BOS TAURUS (BOVINE)	GALACTOSYLTRANSFERASE, UDP-GALACTOSE BETA-D-GALACTOSYL-1,4-N-ACETYL- D-GLUCOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE
2	C, E (A, B)	URIDINE-5'-DIPHOSPHATE-2-DEOXY-2-FLUOROGALACTOSE	non-polymer		568.3	2	Chemie (UPF)
3	D, F (A, B)	MANGANESE (II) ION	non-polymer		54.9	2	Chemie (MN)
4	G, H (A, B)	water	water		18.0	497	Chemie (HOH)

Sequence modifications

A, B: 80 - 368 (UniProt: P14769)

PDB	External Database	Details
Lys 365	Arg 365	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	68124.3
Non-Polymers*	Number of molecules	4
	Total formula weight	1246.5
All*	Total formula weight	69370.8

*Water molecules are not included.