2VFH

Crystal structure of the F96W mutant of Plasmodium falciparum triosephosphate isomerase complexed with 3-phosphoglycerate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	TRIOSEPHOSPHATE ISOMERASE	polymer	248	28036.8	2	UniProt (Q07412) Pfam (PF00121)	PLASMODIUM FALCIPARUM (MALARIAL PARASITE)	TIM, TRIOSE-PHOSPHATE ISOMERASE
2	C, D (A, B)	3-PHOSPHOGLYCERIC ACID	non-polymer		186.1	2	Chemie (3PG)
3	E, F (A, B)	water	water		18.0	440	Chemie (HOH)

Sequence modifications

A, B: 1 - 248 (UniProt: Q07412)

PDB	External Database	Details
Trp 96	Phe 96	engineered mutation
Val 163	Ala 163	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	56073.5
Non-Polymers*	Number of molecules	2
	Total formula weight	372.1
All*	Total formula weight	56445.7

*Water molecules are not included.