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2VF6

Human FDPS synthase in complex with minodronate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
FARNESYL PYROPHOSPHATE SYNTHETASEpolymer37843471.41UniProt (P14324)
Pfam (PF00348)
HOMO SAPIENS (HUMAN)FPP SYNTHETASE, FPS, FARNESYL DIPHOSPHATE SYNTHETASE, DIMETHYLALLYLTRANSTRANSFERASE
2B
(A)
(1-HYDROXY-2-IMIDAZO[1,2-A]PYRIDIN-3-YLETHANE-1,1-DIYL)BIS(PHOSPHONIC ACID)non-polymer322.11Chemie (M0N)
3C, D, E
(A)
MAGNESIUM IONnon-polymer24.33Chemie (MG)
4F
(A)
waterwater18.0171Chemie (HOH)
Sequence modifications
A: -24 - 0 (PDB: 2VF6)
A: 1 - 353 (UniProt: P14324)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight43471.4
Non-Polymers*Number of molecules4
Total formula weight395.1
All*Total formula weight43866.4
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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