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2VDL

Re-refinement of Integrin AlphaIIbBeta3 Headpiece

Replaces:  1TXV
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
INTEGRIN ALPHA-IIBpolymer45249030.41UniProt (P08514)
Pfam (PF01839)
HOMO SAPIENS (HUMAN)PLATELET MEMBRANE GLYCOPROTEIN IIB, GPALPHA IIB, GPIIB, INTEGRIN ALPHA-IIB HEAVY CHAIN
2B
(B)
INTEGRIN BETA-3polymer46150969.71UniProt (P05106)
Pfam (PF17205)
Pfam (PF00362)
Pfam (PF18372)
HOMO SAPIENS (HUMAN)PLATELET MEMBRANE GLYCOPROTEIN IIIA, GPIIIA, CD61 ANTIGEN
3C
(H)
MONOCLONAL ANTIBODY 10E5 HEAVY CHAINpolymer22123766.51MUS MUSCULUS (MOUSE)
4D
(L)
MONOCLONAL ANTIBODY 10E5 LIGHT CHAINpolymer21423332.71MUS MUSCULUS (MOUSE)
5E
(C)
alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched910.81In PDB
GlyTouCan (G21381MC)
6F
(D)
alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched1235.11In PDB
GlyTouCan (G09609EN)
7G, O
(A, B)
GLYCEROLnon-polymer92.12Chemie (GOL)
8H, I, J, K, Q...
(A, B)
CALCIUM IONnon-polymer40.16Chemie (CA)
9L, M, S
(A, B)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.23Chemie (NAG)
10N
(B)
CACODYLATE IONnon-polymer137.01Chemie (CAC)
11P
(B)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
12T, U, V, W
(A, B, H, L)
waterwater18.01129Chemie (HOH)
Sequence modifications
A: 1 - 452 (UniProt: P08514)
PDBExternal DatabaseDetails
Gly 282Ala 313conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight147099.2
BranchedNumber of molecules2
Total formula weight2145.9
Non-Polymers*Number of molecules13
Total formula weight1249.6
All*Total formula weight150494.7
*Water molecules are not included.

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PDB entries from 2024-11-20

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