2VD5

Structure of Human Myotonic Dystrophy Protein Kinase in Complex with the Bisindoylmaleide inhibitor BIM VIII

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	DMPK PROTEIN	polymer	412	46105.4	2	UniProt (Q6P5Z6) Pfam (PF00069) UniProt (by SIFTS) (Q09013)	HOMO SAPIENS (HUMAN)	MYOTONIC DYSTROPHY PROTEIN KINASE
2	C, D (A, B)	3-[1-(3-AMINOPROPYL)-1H-INDOL-3-YL]-4-(1-METHYL-1H-INDOL-3-YL)-1H-PYRROLE-2,5-DIONE	non-polymer		398.5	2	Chemie (BI8)
3	E, F (A, B)	water	water		18.0	9	Chemie (HOH)

Sequence modifications

A, B: 9 - 10 (PDB: 2VD5)
A, B: 11 - 420 (UniProt: Q6P5Z6)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	92210.7
Non-Polymers*	Number of molecules	2
	Total formula weight	796.9
All*	Total formula weight	93007.6

*Water molecules are not included.