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2VD1

Complex structure of prostaglandin D2 synthase at 2.25A.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
GLUTATHIONE-REQUIRING PROSTAGLANDIN D SYNTHASEpolymer19923370.84UniProt (O60760)
Pfam (PF02798)
Pfam (PF14497)
HOMO SAPIENS (HUMAN)GLUTATHIONE-DEPENDENT PGD SYNTHETASE, PROSTAGLANDIN-H2 D-ISOMERASE, HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE, H-PGDS, PROSTAGLANDIN D2 SYNTHASE
2E, H, I, J
(A, B, C, D)
GLUTATHIONEnon-polymer307.34Chemie (GSH)
3F
(B)
4-{[4-(4-fluoro-3-methylphenyl)-1,3-thiazol-2-yl]amino}-2-hydroxybenzoic acidnon-polymer344.41Chemie (D28)
4G
(B)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
5K, L, M, N
(A, B, C, D)
waterwater18.0349Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight93483.3
Non-Polymers*Number of molecules6
Total formula weight1598.0
All*Total formula weight95081.3
*Water molecules are not included.

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PDB entries from 2024-11-06

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