2VCJ
4,5 Diaryl Isoxazole Hsp90 Chaperone Inhibitors: Potential Therapeutic Agents for the Treatment of Cancer
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | HEAT SHOCK PROTEIN HSP 90-ALPHA | polymer | 236 | 26601.8 | 1 | UniProt (P07900) Pfam (PF13589) In PDB | HOMO SAPIENS (HUMAN) | HSP 86, RENAL CARCINOMA ANTIGEN NY-REN-38 |
2 | A | 5-(5-chloro-2,4-dihydroxyphenyl)-N-ethyl-4-[4-(morpholin-4-ylmethyl)phenyl]isoxazole-3-carboxamide | non-polymer | 457.9 | 1 | Chemie (2EQ) | |||
3 | water | water | 18.0 | 137 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 26601.8 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 457.9 | |
All* | Total formula weight | 27059.7 |