2V8Y
Crystallographic and mass spectrometric characterisation of eIF4E with N7-cap derivatives
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, E) | EUKARYOTIC TRANSLATION INITIATION FACTOR 4E | polymer | 217 | 25130.2 | 2 | UniProt (P06730) Pfam (PF01652) | HOMO SAPIENS (HUMAN) | EIF4E, EIF-4E, MRNA CAP-BINDING PROTEIN, EIF-4F 25 KDA SUBUNIT |
| 2 | B, D (B, F) | EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN 1 | polymer | 14 | 1861.2 | 2 | UniProt (Q13541) | HOMO SAPIENS | 4E-BP1, EIF4E-BINDING PROTEIN 1, PHOSPHORYLATED HEAT- AND ACID-STABLE PROTEIN REGULATED BY INSULIN 1, |
| 3 | E, F (A, E) | P-FLUORO-7-BENZYL GUANINE MONOPHOSPHATE | non-polymer | 472.3 | 2 | Chemie (MGV) | |||
| 4 | G, H, I, J (A, B, E, F) | water | water | 18.0 | 312 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 53983.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 944.7 | |
| All* | Total formula weight | 54927.6 |
