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2V8Y

Crystallographic and mass spectrometric characterisation of eIF4E with N7-cap derivatives

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(A, E)
EUKARYOTIC TRANSLATION INITIATION FACTOR 4Epolymer21725130.22UniProt (P06730)
Pfam (PF01652)
HOMO SAPIENS (HUMAN)EIF4E, EIF-4E, MRNA CAP-BINDING PROTEIN, EIF-4F 25 KDA SUBUNIT
2B, D
(B, F)
EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN 1polymer141861.22UniProt (Q13541)HOMO SAPIENS4E-BP1, EIF4E-BINDING PROTEIN 1, PHOSPHORYLATED HEAT- AND ACID-STABLE PROTEIN REGULATED BY INSULIN 1,
3E, F
(A, E)
P-FLUORO-7-BENZYL GUANINE MONOPHOSPHATEnon-polymer472.32Chemie (MGV)
4G, H, I, J
(A, B, E, F)
waterwater18.0312Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight53983.0
Non-Polymers*Number of molecules2
Total formula weight944.7
All*Total formula weight54927.6
*Water molecules are not included.

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PDB entries from 2024-11-06

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