2V8E
Crystal structure of Human Complement Factor H, SCR domains 6-8 (H402 risk variant), in complex with ligand.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | COMPLEMENT FACTOR H | polymer | 187 | 21287.5 | 1 | UniProt (P08603) Pfam (PF00084) | HOMO SAPIENS (HUMAN) | H FACTOR 1, HUMAN COMPLEMENT FACTOR H |
| 2 | B (B) | 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose | branched | 982.8 | 1 | In PDB BIRD (PRD_900013) | sucrose octasulfate | ||
| 3 | C, D (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 4 | E, F, G (A) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 5 | H (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | I (A) | water | water | 18.0 | 46 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 21287.5 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 982.8 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 451.2 | |
| All* | Total formula weight | 22721.5 |
