2V62

Structure of vaccinia-related kinase 2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	SERINE/THREONINE-PROTEIN KINASE VRK2	polymer	345	39259.9	2	UniProt (Q86Y07) Pfam (PF00069)	HOMO SAPIENS (HUMAN)	VACCINIA RELATED PROTEIN KINASE 2
2	C (A)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
3	D (A)	SUCCINIC ACID	non-polymer		118.1	1	Chemie (SIN)
4	E, F, G (A, B)	1,2-ETHANEDIOL	non-polymer		62.1	3	Chemie (EDO)
5	H, I (A, B)	water	water		18.0	334	Chemie (HOH)

Sequence modifications

A, B: 14 - 335 (UniProt: Q86Y07)

PDB	External Database	Details
Met -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
Ser -2	-	expression tag
Ser -1	-	expression tag
Gly 0	-	expression tag
Val 1	-	expression tag
Asp 2	-	expression tag
Leu 3	-	expression tag
Gly 4	-	expression tag
Thr 5	-	expression tag
Glu 6	-	expression tag
Asn 7	-	expression tag
Leu 8	-	expression tag
Tyr 9	-	expression tag
Phe 10	-	expression tag
Gln 11	-	expression tag
Ser 12	-	expression tag
Met 13	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	78519.8
Non-Polymers*	Number of molecules	5
	Total formula weight	328.6
All*	Total formula weight	78848.4

*Water molecules are not included.