2V5R

Structural basis for Dscam isoform specificity

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	DSCAM	polymer	391	43476.0	2	UniProt (Q9NBA1) Pfam (PF07679) Pfam (PF13927) UniProt (by SIFTS) (Q0E9H9) In PDB	DROSOPHILA MELANOGASTER (FRUIT FLY)	DOWN SYNDROME CELL ADHESION MOLECULE DSCAM
2	A, B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	8	Chemie (NAG)
3	B	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)

Sequence modifications

A, B: 1 - 150 (UniProt: Q9NBA1)

PDB	External Database	Details
Ile 103	Ala 138	variant
Ser 105	Tyr 140	variant
Ser 108	Ala 143	variant
Glu 109	Asp 144	variant
Ala 110	Val 145	variant
Asp 111	Asn 146	variant
Asn 112	Lys 147	variant
Tyr 114	His 149	variant
Val 121	Ala 156	variant
Met 123	Ile 158	variant
Glu 126	Leu 161	variant
Tyr 130	Phe 165	variant
Phe 136	Glu 171	variant
Asp 138	Val 173	variant
Leu 139	Ser 174	variant
Leu 141	His 176	variant
Asp 142	Thr 177	variant
Ser 143	Asp 178	variant
Gly 145	Glu 180	variant
Arg 146	Glu 181	variant
Tyr 149	Phe 184	variant

A, B: 153 - 225 (UniProt: Q9NBA1)

PDB	External Database	Details
Ala 153	Gly 186	variant
Thr 156	Tyr 189	variant
Gly 210	Ser 243	variant
Val 212	Ser 245	variant
Arg 213	Pro 246	variant
Val 216	Ile 249	variant
Pro 218	Thr 251	variant
Gln 219	Leu 252	variant
Asp 220	Thr 253	variant
Lys 221	Tyr 254	variant
His 222	Lys 255	variant
Gln 223	Pro 256	variant
Phe 224	Asn 257	variant

A, B: 227 - 391 (UniProt: Q9NBA1)

PDB	External Database	Details
Leu 229	Ser 261	variant
Ala 230	Met 262	variant
Ser 231	Ala 263	variant
Tyr 233	Thr 265	variant
Ser 234	Ala 266	variant
Leu 235	Ile 267	variant
Met 238	Pro 270	variant
Ser 241	Gly 273	variant
Thr 244	Ala 276	variant

A, B: 151 - 152 (PDB: 2V5R)
A, B: 226 - 226 (PDB: 2V5R)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	86952.0
Non-Polymers*	Number of molecules	10
	Total formula weight	1953.9
All*	Total formula weight	88905.9

*Water molecules are not included.