2V5P
COMPLEX STRUCTURE OF HUMAN IGF2R DOMAINS 11-13 BOUND TO IGF-II
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR | polymer | 492 | 54414.2 | 2 | UniProt (P11717) Pfam (PF00878) Pfam (PF00040) | Homo sapiens (Human) | INSULIN-LIKE GROWTH FACTOR II RECEPTOR, CI MAN-6-P RECEPTOR, CI-MPR, M6PR, INSULIN-LIKE GROWTH FACTOR 2 RECEPTOR, IGF-II RECEPTOR, M6P/IGF2 RECEPTOR, M6P/IGF2R, 300 KDA MANNOSE 6-PHOSPHATE RECEPTOR, MPR 300, MPR300, CD222 ANTIGEN |
| 2 | C, D (C, D) | INSULIN-LIKE GROWTH FACTOR II | polymer | 67 | 7484.5 | 2 | UniProt (P01344) Pfam (PF00049) | Homo sapiens (Human) | IGF-II, SOMATOMEDIN A |
| 3 | E (E) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 4 | F, G, H, I, J (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 5 | Chemie (NAG) |
Sequence modifications
A, B: 1508 - 1992 (UniProt: P11717)
A, B: 1993 - 1999 (PDB: 2V5P)
| PDB | External Database | Details |
|---|---|---|
| Ala 1703 | Gly 1703 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 123797.3 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 586.5 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1106.0 | |
| All* | Total formula weight | 125489.9 |
