2V4H

NEMO CC2-LZ domain - 1D5 DARPin complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	NF-KAPPA-B ESSENTIAL MODULATOR	polymer	110	12895.6	2	UniProt (O88522) Pfam (PF16516)	MUS MUSCULUS (HOUSE MOUSE)	NF-KAPPA-B ESSENTIAL MODIFIER, INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE SUBUNIT GAMMA, IKB KINASE-ASSOCIATED PROTEIN 1, NEMO
2	C, D (C, D)	1D5 DARPIN	polymer	136	14924.5	2		SYNTHETIC CONSTRUCT
3	E, F, G, H (A, B, C, D)	water	water		18.0	51	Chemie (HOH)

Sequence modifications

A, B: 251 - 337 (UniProt: O88522)

PDB	External Database	Details
Met 228	-	expression tag
Gly 229	-	expression tag
Ser 230	-	expression tag
Ser 231	-	expression tag
His 232	-	expression tag
His 233	-	expression tag
His 234	-	expression tag
His 235	-	expression tag
His 236	-	expression tag
His 237	-	expression tag
Ser 238	-	expression tag
Ser 239	-	expression tag
Gly 240	-	expression tag
Leu 241	-	expression tag
Val 242	-	expression tag
Pro 243	-	expression tag
Arg 244	-	expression tag
Gly 245	-	expression tag
Ser 246	-	expression tag
His 247	-	expression tag
Met 248	-	expression tag
Ala 249	-	expression tag
Ser 250	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	55640.3
All*	Total formula weight	55640.3

*Water molecules are not included.