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2V0C

LEUCYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH A SULPHAMOYL ANALOGUE OF LEUCYL-ADENYLATE In the synthetic site and an adduct of AMP with 5-Fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole (AN2690) in the editing site

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
AMINOACYL-TRNA SYNTHETASEpolymer878100997.91UniProt (Q7SIE4)
Pfam (PF09334)
Pfam (PF13603)
Pfam (PF00133)
Pfam (PF14795)
Pfam (PF08264)
THERMUS THERMOPHILUSLEUCYL-TRNA SYNTHETASE
2B
(A)
LEUCINEnon-polymer131.21Chemie (LEU)
3C
(A)
[(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDRO-2-FURANYL]METHYL SULFAMATEnon-polymer346.31Chemie (LMS)
4D, E
(A)
ZINC IONnon-polymer65.42Chemie (ZN)
5F
(A)
[(6-AMINO-9H-PURIN-9-YL)-[5-FLUORO-1,3-DIHYDRO-1-HYDROXY-2,1-BENZOXABOROLE]-4'YL]METHYL DIHYDROGEN PHOSPHATEnon-polymer480.11Chemie (ANZ)
6G, H, I, J, K
(A)
SULFATE IONnon-polymer96.15Chemie (SO4)
7L
(A)
waterwater18.0684Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight100997.9
Non-Polymers*Number of molecules10
Total formula weight1568.8
All*Total formula weight102566.7
*Water molecules are not included.

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PDB entries from 2025-06-11

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