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2UZL

Crystal structure of human CDK2 complexed with a thiazolidinone inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, CCELL DIVISION PROTEIN KINASE 2polymer29834056.52UniProt (P24941)
Pfam (PF00069)
In PDB
HOMO SAPIENS (HUMAN)P33 PROTEIN KINASE, CYCLIN DEPENDENT KINASE 2
2B, DCYCLIN A2polymer25829624.32UniProt (P20248)
Pfam (PF00134)
Pfam (PF02984)
In PDB
HOMO SAPIENS (HUMAN)CYCLIN-A
3A, C4-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}-2-(TRIFLUOROMETHYL)BENZENESULFONAMIDEnon-polymer417.42Chemie (C94)
4waterwater18.0413Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight127361.5
Non-Polymers*Number of molecules2
Total formula weight834.8
All*Total formula weight128196.3
*Water molecules are not included.

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PDB entries from 2024-09-18

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