2UZL
Crystal structure of human CDK2 complexed with a thiazolidinone inhibitor
Experimental procedure
Experimental method | SINGLE WAVELENGTH |
Source type | SYNCHROTRON |
Source details | ESRF BEAMLINE ID14-4 |
Synchrotron site | ESRF |
Beamline | ID14-4 |
Temperature [K] | 100 |
Detector technology | CCD |
Collection date | 2003-09-22 |
Detector | ADSC CCD |
Spacegroup name | C 1 2 1 |
Unit cell lengths | 211.604, 73.285, 152.367 |
Unit cell angles | 90.00, 129.33, 90.00 |
Refinement procedure
Resolution | 15.000 - 2.400 |
R-factor | 0.206 |
Rwork | 0.203 |
R-free | 0.26300 |
Structure solution method | OTHER |
RMSD bond length | 0.013 |
RMSD bond angle | 1.991 |
Data reduction software | DENZO |
Data scaling software | SCALEPACK |
Refinement software | REFMAC (5.2.0019) |
Data quality characteristics
Overall | |
Low resolution limit [Å] | 30.000 |
High resolution limit [Å] | 2.400 |
Rmerge | 0.130 |
Number of reflections | 61935 |
<I/σ(I)> | 7.2 |
Completeness [%] | 88.2 |
Redundancy | 2.7 |
Crystallization Conditions
crystal ID | method | pH | temperature | details |
1 | VAPOR DIFFUSION | 7 | 277 | VAPOUR DIFFUSION AT 4 DEG C, 0.1 M HEPES PH 7.0, 1M LITHIUM SULPHATE |