2UZK

Crystal structure of the human FOXO3a-DBD bound to DNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	FORKHEAD BOX PROTEIN O3A	polymer	97	11019.5	2	UniProt (O43524) Pfam (PF00250)	HOMO SAPIENS (HUMAN)	FORKHEAD IN RHABDOMYOSARCOMA-LIKE 1, AF6Q21 PROTEIN
2	B, D (B, D)	5'-D(*CP*TP*AP*TP*GP*TP*AP*AP*AP*CP*AP*AP*C)-3'	polymer	13	3943.6	2		HOMO SAPIENS	FOXO CONSENSUS BINDING SEQUENCE
3	E, F (E, F)	5'-D(*GP*TP*TP*GP*TP*TP*TP*AP*CP*AP*TP*AP*G)-3'	polymer	13	3996.6	2		HOMO SAPIENS	FOXO CONSENSUS BINDING SEQUENCE
4	G, H, I, J, K... (A, B, C, D, E...)	water	water		18.0	209	Chemie (HOH)

Sequence modifications

A, C: 157 - 157 (PDB: 2UZK)
A, C: 158 - 253 (UniProt: O43524)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	37919.4
All*	Total formula weight	37919.4

*Water molecules are not included.