2UZ3

Crystal Structure of Thymidine Kinase with dTTP from U. urealyticum

Replaces:  1XMR

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	THYMIDINE KINASE	polymer	243	27611.6	4	UniProt (Q9PPP5) Pfam (PF00265)	UREAPLASMA UREALYTICUM
2	E, G, J, L (A, B, C, D)	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
3	F, I, K, N (A, B, C, D)	THYMIDINE-5'-TRIPHOSPHATE	non-polymer		482.2	4	Chemie (TTP)
4	H, M (B, D)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
5	O, P, Q, R (A, B, C, D)	water	water		18.0	144	Chemie (HOH)

Sequence modifications

A, B, C, D: -19 - 0 (PDB: 2UZ3)
A, B, C, D: 1 - 223 (UniProt: Q9PPP5)

PDB	External Database	Details
Phe 16	Leu 16	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	110446.4
Non-Polymers*	Number of molecules	10
	Total formula weight	2238.9
All*	Total formula weight	112685.3

*Water molecules are not included.