2UYI
Crystal structure of KSP in complex with ADP and thiophene containing inhibitor 33
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | KINESIN-LIKE PROTEIN KIF11 | polymer | 368 | 41055.6 | 2 | UniProt (P52732) Pfam (PF00225) In PDB | HOMO SAPIENS (HUMAN) | KINESIN-RELATED MOTOR PROTEIN EG5, KINESIN-LIKE SPINDLE PROTEIN HKSP, THYROID RECEPTOR-INTERACTING PROTEIN 5, TRIP-5, KINESIN-LIKE PROTEIN 1, KINESIN SPINDLE PROTEIN |
| 2 | A, B | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) | |||
| 3 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | A, B | (5R)-N,N-DIETHYL-5-METHYL-2-[(THIOPHEN-2-YLCARBONYL)AMINO]-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE | non-polymer | 376.5 | 2 | Chemie (K02) | |||
| 5 | water | water | 18.0 | 276 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 82111.2 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1656.1 | |
| All* | Total formula weight | 83767.2 |
