2UYC

HhaI DNA methyltransferase R163N mutant complex with 13mer GCGC-GMGC oligonucleotide and SAH

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	MODIFICATION METHYLASE HHAI	polymer	327	36999.1	1	UniProt (P05102)	HAEMOPHILUS HAEMOLYTICUS	CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI, MHHAI, HHAI DNA METHYLTRANSFERASE
2	B (C)	5'-D(*TP*GP*GP*AP*TP*GP*5CMP*GP*CP*TP *GP*AP*C)-3'	polymer	13	4021.6	1		synthetic construct
3	C (D)	5'-D(*GP*TP*CP*AP*GP*CP*GP*CP*AP*TP *CP*C)-3'	polymer	12	3623.4	1		synthetic construct
4	D (A)	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	1	Chemie (SAH) PubChem (16760024) PubChem (193) PubChem (25210495) PubChem (13792) PubChem (177678424) PubChem (44361184) PubChem (21125603) PubChem (46936206) PubChem (50989525) PubChem (25203782) PubChem (51380914) PubChem (52224398) PubChem (189149) PubChem (57544532) PubChem (439155) PubChem (59046843) PubChem (59170628) PubChem (59576228) PubChem (66805708) PubChem (70689219) PubChem (70702054) PubChem (70832431) PubChem (52224400) PubChem (5284331) PubChem (6419189) PubChem (118374891) PubChem (118560068) PubChem (71170554) PubChem (13231890) PubChem (164157219) PubChem (126969526) PubChem (129105892) PubChem (143518505) PubChem (154578335) PubChem (163054214) PubChem (163335525)
5	E, F, G, H, I... (A)	SULFATE ION	non-polymer		96.1	6	Chemie (SO4)
6	K, L, M, N, O (A)	GLYCEROL	non-polymer		92.1	5	Chemie (GOL) PubChem (753)
7	P, Q, R (A, C, D)	water	water		18.0	234	Chemie (HOH)

Sequence modifications

A: 1 - 327 (UniProt: P05102)

PDB	External Database	Details
Asn 163	Arg 163	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	44644.1
Non-Polymers*	Number of molecules	12
	Total formula weight	1421.3
All*	Total formula weight	46065.4

*Water molecules are not included.