2UXX
Human LSD1 Histone Demethylase-CoREST in complex with an FAD- tranylcypromine adduct
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | LYSINE-SPECIFIC HISTONE DEMETHYLASE 1 | polymer | 666 | 74126.8 | 1 | UniProt (O60341) Pfam (PF04433) Pfam (PF01593) | HOMO SAPIENS (HUMAN) | FLAVIN-CONTAINING AMINE OXIDASE DOMAIN-CONTAINING PROTEIN 2, BRAF35-HDAC COMPLEX PROTEIN BHC110, LYSINE- SPECIFIC DEMETHYLASE 1 |
| 2 | B (B) | REST COREPRESSOR 1 | polymer | 235 | 26425.7 | 1 | UniProt (Q9UKL0) Pfam (PF20878) Pfam (PF00249) | HOMO SAPIENS (HUMAN) | PROTEIN COREST, NUCLEAR RECEPTOR COREPRESSOR 2 |
| 3 | C (A) | FAD-trans-2-Phenylcyclopropylamine Adduct | non-polymer | 919.7 | 1 | Chemie (FAJ) | |||
| 4 | D, E (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | F (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | G, H (A, B) | water | water | 18.0 | 8 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 100552.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1139.4 | |
| All* | Total formula weight | 101691.9 |
