2UW9

STRUCTURE OF PKB-BETA (AKT2) COMPLEXED WITH 4-(4-chloro-phenyl)-4-(4-(1H-pyrazol-4-yl)-phenyl)-piperidine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	RAC-BETA SERINE/THREONINE-PROTEIN KINASE	polymer	342	39860.4	1	UniProt (P31751) Pfam (PF00069) Pfam (PF00433)	HOMO SAPIENS (HUMAN)	PROTEIN KINASE B-BETA, RAC-PK-BETA, PROTEIN KINASE AKT-2, PROTEIN KINASE B, BETA, PKB BETA
2	B (C)	GLYCOGEN SYNTHASE KINASE-3 BETA	polymer	10	1123.2	1	UniProt (P49841)	HOMO SAPIENS	GSK3-BETA PEPTIDE, GSK-3 BETA
3	C (A)	4-(4-CHLOROPHENYL)-4-[4-(1H-PYRAZOL-4-YL)PHENYL]PIPERIDINE	non-polymer		337.8	1	Chemie (GVP)
4	D, E (A, C)	water	water		18.0	162	Chemie (HOH)

Sequence modifications

A: 141 - 145 (PDB: 2UW9)
A: 465 - 479 (PDB: 2UW9)
A: 146 - 464 (UniProt: P31751)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	40983.6
Non-Polymers*	Number of molecules	1
	Total formula weight	337.8
All*	Total formula weight	41321.4

*Water molecules are not included.