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2ROZ

Structure of the C-terminal PID Domain of Fe65L1 Complexed with the Cytoplasmic Tail of APP Reveals a Novel Peptide Binding Mode

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
peptide from Amyloid beta A4 proteinpolymer323836.21UniProt (P12023)
Pfam (PF10515)
APP-derived_32-mer_peptide
2B
(B)
Amyloid beta A4 precursor protein-binding family B member 2polymer13614750.51UniProt (Q9DBR4)
Pfam (PF00640)
Mus musculus (mouse)Fe65L1
Sequence modifications
B: 8 - 130 (UniProt: Q9DBR4)
PDBExternal DatabaseDetails
Gly 1-expression tag
Ser 2-expression tag
Ser 3-expression tag
Gly 4-expression tag
Ser 5-expression tag
Ser 6-expression tag
Gly 7-expression tag
Ser 131-expression tag
Gly 132-expression tag
Pro 133-expression tag
Ser 134-expression tag
Ser 135-expression tag
Gly 136-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight18586.7
All*Total formula weight18586.7
*Water molecules are not included.

243911

PDB entries from 2025-10-29

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